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Motif ID: TLX1..3_NFIC{dimer}.p2

Z-value: 1.011

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chrX_-_128788913	1.739	NM_017413	APLN	apelin
chr11_-_71752099	1.392		NUMA1	nuclear mitotic apparatus protein 1
chr7_+_73624328	1.339		LAT2	linker for activation of T cells family, member 2
chr7_+_73624347	1.281		LAT2	linker for activation of T cells family, member 2
chr19_+_10397642	1.275	NM_001039132 NM_001544 NM_022377	ICAM4	intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
chr1_+_79086087	1.175	NM_006820	IFI44L	interferon-induced protein 44-like
chr3_+_126261178	1.150		CHST13	carbohydrate (chondroitin 4) sulfotransferase 13
chr19_-_41356193	1.100	NM_000762	CYP2A6	cytochrome P450, family 2, subfamily A, polypeptide 6
chr17_-_39143252	0.911	NM_182497	KRT40	keratin 40
chr6_-_46922533	0.877	NM_015234	GPR116	G protein-coupled receptor 116
chr1_-_205391180	0.854	NM_001001552 NM_001199050 NM_001199051 NM_001199052	LEMD1	LEM domain containing 1
chr8_-_10512616	0.847	NM_178857	RP1L1	retinitis pigmentosa 1-like 1
chr3_+_100328432	0.826	NM_032787	GPR128	G protein-coupled receptor 128
chr17_-_3182267	0.825	NM_002551	OR3A2	olfactory receptor, family 3, subfamily A, member 2
chr7_+_73624086	0.756	NM_014146 NM_032463 NM_032464	LAT2	linker for activation of T cells family, member 2
chr19_+_15783827	0.733	NM_023944	CYP4F12	cytochrome P450, family 4, subfamily F, polypeptide 12
chr5_-_73937248	0.732	NM_003633	ENC1	ectodermal-neural cortex 1 (with BTB-like domain)
chrX_-_53310748	0.721	NM_001243197 NM_015075	IQSEC2	IQ motif and Sec7 domain 2
chr17_+_48503607	0.715		ACSF2	acyl-CoA synthetase family member 2
chr14_+_24540742	0.700	NM_006032	CPNE6	copine VI (neuronal)
chr17_+_48503518	0.679	NM_025149	ACSF2	acyl-CoA synthetase family member 2
chr5_-_111093030	0.643	NM_001142482 NM_001142481	C5orf13	chromosome 5 open reading frame 13
chr5_-_111092918	0.637	NM_004772	C5orf13	chromosome 5 open reading frame 13
chr16_-_27899477	0.621	NM_144675	GSG1L	GSG1-like
chr7_+_22767101	0.620		IL6	interleukin 6 (interferon, beta 2)
chr5_-_111093251	0.592	NM_001142479 NM_001142480 NM_001142478	C5orf13	chromosome 5 open reading frame 13
chr2_-_37899227	0.577	NM_006449	CDC42EP3	CDC42 effector protein (Rho GTPase binding) 3
chr1_+_203595897	0.552	NM_001001396 NM_001684	ATP2B4	ATPase, Ca++ transporting, plasma membrane 4
chr2_-_216300444	0.541		FN1	fibronectin 1
chr12_-_53228061	0.538	NM_175834	KRT79	keratin 79
chr11_+_1244292	0.537	NM_002458	MUC5B	mucin 5B, oligomeric mucus/gel-forming
chr2_-_217560247	0.536	NM_000599	IGFBP5	insulin-like growth factor binding protein 5
chr7_+_1127722	0.533	NM_001098201	GPER	G protein-coupled estrogen receptor 1
chr2_-_7005764	0.531	NM_207315	CMPK2	cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr11_-_10715160	0.530		MRVI1	murine retrovirus integration site 1 homolog
chr1_+_177140530	0.522	NM_021165	FAM5B	family with sequence similarity 5, member B
chr12_+_100867550	0.521	NM_001206977 NM_001206978 NM_001206979 NM_005123	NR1H4	nuclear receptor subfamily 1, group H, member 4
chr17_+_72439187	0.517		GPRC5C	G protein-coupled receptor, family C, group 5, member C
chr11_-_65325391	0.515		LTBP3	latent transforming growth factor beta binding protein 3
chr1_-_55089068	0.510	NM_176782	FAM151A	family with sequence similarity 151, member A
chr10_-_128077072	0.510	NM_003474 NM_021641	ADAM12	ADAM metallopeptidase domain 12
chr17_+_7211693	0.509	NM_001143762	EIF5A	eukaryotic translation initiation factor 5A
chr5_-_172198160	0.508	NM_004417	DUSP1	dual specificity phosphatase 1
chr11_-_35441099	0.506	NM_004171	SLC1A2	solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr11_-_10715297	0.502		MRVI1	murine retrovirus integration site 1 homolog
chr2_+_7017795	0.499	NM_080657	RSAD2	radical S-adenosyl methionine domain containing 2
chr5_-_111092865	0.498		C5orf13	chromosome 5 open reading frame 13
chr1_-_86622107	0.498	NM_152890	COL24A1	collagen, type XXIV, alpha 1
chr15_-_65503786	0.496	NM_003613	CILP	cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
chr17_-_76921076	0.495		TIMP2	TIMP metallopeptidase inhibitor 2
chr22_+_43808011	0.492	NM_001044370	MPPED1	metallophosphoesterase domain containing 1
chr13_+_114321469	0.490	NM_002929	GRK1	G protein-coupled receptor kinase 1
chrX_+_49126299	0.488	NM_001184745 NM_033215	PPP1R3F	protein phosphatase 1, regulatory subunit 3F
chr17_+_7210929	0.487		EIF5A	eukaryotic translation initiation factor 5A
chr17_+_1633754	0.478		WDR81	WD repeat domain 81
chr7_+_116165089	0.474		CAV1	caveolin 1, caveolae protein, 22kDa
chr11_+_124481451	0.472	NM_052959	PANX3	pannexin 3
chr12_+_100867739	0.471		NR1H4	nuclear receptor subfamily 1, group H, member 4
chr11_-_65326129	0.468		LTBP3	latent transforming growth factor beta binding protein 3
chr7_+_143013218	0.467	NM_000083	CLCN1	chloride channel 1, skeletal muscle
chr4_-_109684053	0.466	NM_001146590 NM_001146627 NM_031279	AGXT2L1	alanine-glyoxylate aminotransferase 2-like 1
chr10_+_17271277	0.465		VIM	vimentin
chr1_+_203595929	0.464		ATP2B4	ATPase, Ca++ transporting, plasma membrane 4
chr6_-_30043547	0.463	NM_170769 NM_025236	RNF39	ring finger protein 39
chr9_-_130616957	0.463		ENG	endoglin
chr17_-_76921453	0.457	NM_003255	TIMP2	TIMP metallopeptidase inhibitor 2
chr22_-_24640850	0.452	NM_001099781 NM_001099782 NM_004121	GGT5	gamma-glutamyltransferase 5
chr14_+_24867926	0.451	NM_025081	NYNRIN	NYN domain and retroviral integrase containing
chr10_+_17271276	0.445		VIM	vimentin
chr10_+_17271302	0.445		VIM	vimentin
chr7_+_22766765	0.444	NM_000600	IL6	interleukin 6 (interferon, beta 2)
chr19_-_41388656	0.443	NM_000764 NM_030589	CYP2A7	cytochrome P450, family 2, subfamily A, polypeptide 7
chr11_-_35441501	0.443	NM_001195728 NM_001252652	SLC1A2	solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr6_-_31550065	0.432	NM_002341 NM_009588	LTB	lymphotoxin beta (TNF superfamily, member 3)
chr14_-_76447445	0.430		TGFB3	transforming growth factor, beta 3
chr6_+_167738573	0.429	NM_031949	TTLL2	tubulin tyrosine ligase-like family, member 2
chr20_+_31669317	0.421	NM_182519	BPIFB4	BPI fold containing family B, member 4
chr19_-_8675559	0.415	NM_030957	ADAMTS10	ADAM metallopeptidase with thrombospondin type 1 motif, 10
chr1_-_39407449	0.415	NM_017821	RHBDL2	rhomboid, veinlet-like 2 (Drosophila)
chr7_-_27187367	0.410	NM_024014	HOXA6	homeobox A6
chr9_+_136399877	0.397	NM_014694	ADAMTSL2	ADAMTS-like 2
chr9_-_130617009	0.396	NM_000118 NM_001114753	ENG	endoglin
chr16_-_51185150	0.395	NM_002968	SALL1	sal-like 1 (Drosophila)
chr8_+_22022872	0.393		BMP1	bone morphogenetic protein 1
chr2_-_37898768	0.392		CDC42EP3	CDC42 effector protein (Rho GTPase binding) 3
chr12_-_8815479	0.391		MFAP5	microfibrillar associated protein 5
chr3_+_186915273	0.390	NM_153708	RTP1	receptor (chemosensory) transporter protein 1
chr1_+_155023781	0.389		ADAM15	ADAM metallopeptidase domain 15
chr22_+_30792929	0.388	NM_001204204 NM_012429 NM_033382	SEC14L2	SEC14-like 2 (S. cerevisiae)
chr17_-_27948345	0.386	NM_032854	CORO6	coronin 6
chr10_-_13276327	0.386	NM_145314	UCMA	upper zone of growth plate and cartilage matrix associated
chr10_+_17271341	0.383		VIM	vimentin
chr8_+_22022677	0.375		BMP1	bone morphogenetic protein 1
chr16_+_2867163	0.374	NM_006799 NM_144956 NM_144957	PRSS21	protease, serine, 21 (testisin)
chr12_-_56106061	0.372	NM_001144997	ITGA7	integrin, alpha 7
chr11_-_62457001	0.372		LRRN4CL	LRRN4 C-terminal like
chr11_+_65268313	0.371		MALAT1	metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
chr9_-_130616760	0.371		ENG	endoglin
chr15_-_35087748	0.370	NM_005159	ACTC1	actin, alpha, cardiac muscle 1
chr2_-_218843541	0.368		TNS1	tensin 1
chr22_-_39640956	0.366	NM_002608	PDGFB	platelet-derived growth factor beta polypeptide
chr2_+_223536362	0.363	NM_058165	MOGAT1	monoacylglycerol O-acyltransferase 1
chrX_+_106161589	0.359	NM_001171095	CLDN2	claudin 2
chr19_-_16045669	0.354	NM_001128932 NM_021187	CYP4F11	cytochrome P450, family 4, subfamily F, polypeptide 11
chr7_-_100076754	0.352	NM_030935	TSC22D4	TSC22 domain family, member 4
chr20_-_60942300	0.349	NM_005560	LAMA5	laminin, alpha 5
chr16_+_2867227	0.343		PRSS21	protease, serine, 21 (testisin)
chr5_-_146460991	0.342	NM_181677 NM_181678	PPP2R2B	protein phosphatase 2, regulatory subunit B, beta
chr12_+_18891040	0.341	NM_033328	CAPZA3	capping protein (actin filament) muscle Z-line, alpha 3
chr5_+_72251869	0.341
chr6_+_132129195	0.340		ENPP1	ectonucleotide pyrophosphatase/phosphodiesterase 1
chr1_+_203596222	0.340		ATP2B4	ATPase, Ca++ transporting, plasma membrane 4
chr11_-_64764388	0.340	NM_138456	BATF2	basic leucine zipper transcription factor, ATF-like 2
chr11_-_65325632	0.338	NM_001130144 NM_001164266 NM_021070	LTBP3	latent transforming growth factor beta binding protein 3
chr11_+_61976139	0.338	NM_002407	SCGB2A1	secretoglobin, family 2A, member 1
chr9_-_132515290	0.336	NM_004878	PTGES	prostaglandin E synthase
chr2_-_192711651	0.336		SDPR	serum deprivation response
chr11_+_560868	0.336	NM_001143993	RASSF7	Ras association (RalGDS/AF-6) domain family (N-terminal) member 7
chr2_+_128293312	0.334	NM_001080527	MYO7B	myosin VIIB
chr9_+_116356199	0.333	NM_144489	RGS3	regulator of G-protein signaling 3
chr19_+_35630391	0.332	NM_005031	FXYD1	FXYD domain containing ion transport regulator 1
chr8_+_22022644	0.331	NM_001199 NM_006129	BMP1	bone morphogenetic protein 1
chr4_-_103266396	0.328	NM_001135147	SLC39A8	solute carrier family 39 (zinc transporter), member 8
chr19_-_35633354	0.327		LGI4	leucine-rich repeat LGI family, member 4
chr16_+_57406398	0.327	NM_002996	CX3CL1	chemokine (C-X3-C motif) ligand 1
chr19_+_49547101	0.323	NM_033043	CGB CGB5	chorionic gonadotropin, beta polypeptide chorionic gonadotropin, beta polypeptide 5
chr9_+_74764266	0.322	NM_001242505 NM_001242506 NM_004293	GDA	guanine deaminase
chr21_+_43823970	0.321	NM_001001895 NM_001243467 NM_018961	UBASH3A	ubiquitin associated and SH3 domain containing A
chr5_+_38445577	0.315	NM_182801	EGFLAM	EGF-like, fibronectin type III and laminin G domains
chr7_+_142495142	0.315
chr1_-_160039946	0.314	NM_002241	KCNJ10	potassium inwardly-rectifying channel, subfamily J, member 10
chr14_-_76448091	0.312	NM_003239	TGFB3	transforming growth factor, beta 3
chr9_+_116356407	0.309		RGS3	regulator of G-protein signaling 3
chrX_+_106171328	0.308		CLDN2	claudin 2
chr12_-_8815370	0.308	NM_003480	MFAP5	microfibrillar associated protein 5
chr17_-_45899133	0.307	NM_145798	OSBPL7	oxysterol binding protein-like 7
chrX_-_154114431	0.304	NM_019863	F8	coagulation factor VIII, procoagulant component
chr8_+_144295067	0.304	NM_178172	GPIHBP1	glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1
chr7_-_99573637	0.304	NM_001185	AZGP1	alpha-2-glycoprotein 1, zinc-binding
chr4_-_103245468	0.301	NM_001135148	SLC39A8	solute carrier family 39 (zinc transporter), member 8
chr9_+_74764382	0.300		GDA	guanine deaminase
chr1_+_154377847	0.299		IL6R	interleukin 6 receptor
chr10_+_17270469	0.298		VIM	vimentin
chr11_-_62457370	0.297	NM_203422	LRRN4CL	LRRN4 C-terminal like
chr15_-_59665069	0.293	NM_004998	MYO1E	myosin IE
chr11_+_120110902	0.291	NM_014352	POU2F3	POU class 2 homeobox 3
chr4_-_48014960	0.291	NM_000087	CNGA1	cyclic nucleotide gated channel alpha 1
chr1_-_22263676	0.290	NM_005529	HSPG2	heparan sulfate proteoglycan 2
chr17_+_7211260	0.289	NM_001143761	EIF5A	eukaryotic translation initiation factor 5A
chr17_+_7184978	0.288	NM_001042	SLC2A4	solute carrier family 2 (facilitated glucose transporter), member 4
chr21_+_46875402	0.287	NM_030582	COL18A1	collagen, type XVIII, alpha 1
chr10_+_106034886	0.285	NM_001191014 NM_001191015	GSTO2	glutathione S-transferase omega 2
chr9_+_90112754	0.283	NM_004938	DAPK1	death-associated protein kinase 1
chr10_+_124320180	0.282	NM_004406 NM_007329 NM_017579	DMBT1	deleted in malignant brain tumors 1
chr11_-_35440514	0.281		SLC1A2	solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr1_+_154378044	0.280		IL6R	interleukin 6 receptor
chr2_+_220325533	0.280	NM_001173476	SPEG	SPEG complex locus
chr1_+_27153130	0.280	NM_032283	ZDHHC18	zinc finger, DHHC-type containing 18
chr19_+_56511090	0.278	NM_153447	NLRP5	NLR family, pyrin domain containing 5
chr3_+_46742822	0.278	NM_147196	TMIE	transmembrane inner ear
chr12_+_21168629	0.277	NM_001009562	SLCO1B7	solute carrier organic anion transporter family, member 1B7 (non-functional)
chr15_-_90347534	0.277		ANPEP	alanyl (membrane) aminopeptidase
chr9_-_130616592	0.274		ENG	endoglin
chr22_-_30960875	0.272	NM_004861	GAL3ST1	galactose-3-O-sulfotransferase 1
chr22_+_26565623	0.270		SEZ6L	seizure related 6 homolog (mouse)-like
chr9_+_74764394	0.268		GDA	guanine deaminase
chr15_-_90347173	0.268		ANPEP	alanyl (membrane) aminopeptidase
chr11_+_46722564	0.267	NM_001184751	ZNF408	zinc finger protein 408
chr15_+_75041182	0.266	NM_000761	CYP1A2	cytochrome P450, family 1, subfamily A, polypeptide 2
chr12_-_109025825	0.266	NM_001206609	SELPLG	selectin P ligand
chr17_-_48474864	0.265		LRRC59	leucine rich repeat containing 59
chr17_+_7210841	0.263	NM_001970	EIF5A	eukaryotic translation initiation factor 5A
chrX_+_99899162	0.261	NM_014467	SRPX2	sushi-repeat containing protein, X-linked 2
chr15_-_40630272	0.259		C15orf52	chromosome 15 open reading frame 52
chr11_+_819563	0.259		PNPLA2	patatin-like phospholipase domain containing 2
chr7_-_37024664	0.258	NM_001039459	ELMO1	engulfment and cell motility 1
chr11_+_63974190	0.256		FERMT3	fermitin family member 3
chr13_+_111767586	0.255	NM_001113511 NM_001113512 NM_145735	ARHGEF7	Rho guanine nucleotide exchange factor (GEF) 7
chr5_-_176831183	0.255		F12	coagulation factor XII (Hageman factor)
chr15_+_66994669	0.254	NM_005585	SMAD6	SMAD family member 6
chr16_+_23568833	0.253	NM_019116	UBFD1	ubiquitin family domain containing 1
chr9_+_139557378	0.251	NM_016215	EGFL7	EGF-like-domain, multiple 7
chr6_-_94129059	0.250	NM_004440	EPHA7	EPH receptor A7
chr15_-_40213087	0.249	NM_007223	GPR176	G protein-coupled receptor 176
chr18_-_19180657	0.247	NM_052911	ESCO1	establishment of cohesion 1 homolog 1 (S. cerevisiae)
chr19_+_35849487	0.246	NM_005304	FFAR3	free fatty acid receptor 3
chr7_+_116165043	0.246	NM_001172895	CAV1	caveolin 1, caveolae protein, 22kDa
chr1_+_22979681	0.246	NM_000491	C1QB	complement component 1, q subcomponent, B chain
chr5_+_150020201	0.245	NM_001109974 NM_007286	SYNPO	synaptopodin
chr14_-_75330535	0.244	NM_001080408 NM_001243007	PROX2	prospero homeobox 2
chr5_+_131746579	0.244		C5orf56	chromosome 5 open reading frame 56
chr17_+_57642885	0.243	NM_001166301 NM_024612	DHX40	DEAH (Asp-Glu-Ala-His) box polypeptide 40
chr21_+_45937499	0.242		C21orf90	chromosome 21 open reading frame 90
chr1_-_161039413	0.242		ARHGAP30	Rho GTPase activating protein 30
chr1_-_115300615	0.240	NM_001007553 NM_001130523 NM_001242891 NM_001242892 NM_001242893 NM_007158	CSDE1	cold shock domain containing E1, RNA-binding
chr8_-_13134028	0.237		DLC1	deleted in liver cancer 1
chr17_+_27369917	0.236	NM_016518	PIPOX	pipecolic acid oxidase
chr1_-_202130677	0.236	NM_001199797 NM_002832	PTPN7	protein tyrosine phosphatase, non-receptor type 7
chr12_-_8815266	0.236		MFAP5	microfibrillar associated protein 5
chr17_-_76921205	0.233		TIMP2	TIMP metallopeptidase inhibitor 2

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.32	9.96e-04	GO:0032502	developmental process
1.35	1.46e-03	GO:0048856	anatomical structure development
1.32	2.96e-03	GO:0007275	multicellular organismal development
1.36	4.09e-03	GO:0048731	system development
1.23	6.80e-03	GO:0032501	multicellular organismal process
1.43	1.78e-02	GO:0048583	regulation of response to stimulus
17.57	2.36e-02	GO:0048755	branching morphogenesis of a nerve
1.49	2.48e-02	GO:0009653	anatomical structure morphogenesis
1.48	4.80e-02	GO:0009966	regulation of signal transduction

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.85	2.43e-07	GO:0044421	extracellular region part
1.50	1.29e-05	GO:0005576	extracellular region
2.24	7.74e-05	GO:0031012	extracellular matrix
2.36	9.14e-05	GO:0005578	proteinaceous extracellular matrix
1.42	3.61e-04	GO:0044459	plasma membrane part
1.72	1.13e-03	GO:0005615	extracellular space
2.15	5.15e-03	GO:0015629	actin cytoskeleton
1.97	7.97e-03	GO:0009986	cell surface

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
12.55	5.85e-03	GO:0034713	type I transforming growth factor beta receptor binding
1.55	1.96e-02	GO:0005102	receptor binding